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AACR: Markers Hint at Who Cancer Treatments Could Help
Several abstracts involving
potential biomarkers of prognosis in cancer treatment were
presented at a press briefing Nov. 18 at the American
Association for Cancer Research -- National Cancer Institute --
European Organisation for Research and Treatment of Cancer
International Conference, "Molecular Targets and Cancer
Therapeutics," held from Nov. 15 to 19 in Boston.
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AACR: Novel Breast Cancer Therapy Exploits Autophagy Response
Targeting a cancer cell's heat
shock response protein 70 with panobinostat to induce autophagy
in the stressed cell, and then introducing an autophagy
inhibitor to force the cell to die off, may be an effective
novel treatment strategy for breast cancer, according to a Nov.
16 press briefing presented at the American Association for
Cancer Research -- National Cancer Institute -- European
Organisation for Research and Treatment of Cancer International
Conference, "Molecular Targets and Cancer Therapeutics," held
from Nov. 15 to 19 in Boston.
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Cervical Cancer Screening Guidelines Updated
Women should not start getting
routine cervical cancer tests until age 21, and then they
should repeat them every two years instead of annually though
age 30, according to new guidelines from the American College
of Obstetricians and Gynecologists published in Obstetrics
& Gynecology.
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County-Level Data Reveals Diabetes, Obesity Hot Spots
Model-based estimates can give
meaningful and valid county-level data on the prevalence of
diabetes and obesity that is useful for local public health
officials, according to a report published in the Nov. 20 issue
of the U.S. Centers for Disease Control and Prevention's
Morbidity and Mortality Weekly Report.
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Deformational Plagiocephaly Risk Factors Evaluated
Children's sleep position appears
correlated with the location of deformational plagiocephaly,
which typically presents as a flat spot on the back of the
skull, according to research published online Nov. 16 in
Pediatrics.
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Efficacy of Transradial Catheterization Studied
In patients undergoing coronary
catheterization, transradial coronary angiography and
angioplasty is as safe and effective as the transfemoral
approach, according to a study in the November issue of the
Journal of the American College of Cardiology:
Cardiovascular Interventions.
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Embryonic Stem Cells Show Potential for Skin Substitute
Human embryonic stem cells can be
used to create a stratified epithelium resembling normal human
epidermis, a finding that has potential implications in
producing temporary skin replacement for burn patients,
according to research published in the Nov. 21 issue of The
Lancet.
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Laser-Treated Corneas Found Suitable for Donor Tissue
Laser in situ keratomileusis and
photorefractive keratectomy are not likely associated with any
significant long-term effect on the corneal endothelium, and
may be used as donor tissue, according to a study published in
the November issue of the Archives of Ophthalmology.
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New Algorithms Help Predict Osteoporotic Fracture Risk
Two new algorithms,
QFractureScores, may accurately predict fracture risk without
laboratory measurements, and may be suitable for use in both
clinical settings and for self assessment, according to a U.K.
study published online Nov. 19 in BMJ.
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Pandemic Influenza May Hurt Economy in United Kingdom
Although pandemic influenza may
only decrease the gross domestic product by up to 4.3 percent
in the United Kingdom, school closures and absenteeism from
work due to government regulations or fear of infection may
negatively impact the economy and potentially increase the
effect of the recession, according to a study published Nov. 19
in BMJ.
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Patients With Limited English Present Practice Challenges
Important practice setting
differences exist in the use and availability of trained
medical interpreters and telephone interpretation services for
communicating with limited English proficient patients,
according to a study published online Oct. 29 in Health
Services Research.
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Salmeterol Found Similarly Effective in Asthma Genotypes
Outcomes in the long-acting
β2 agonist in asthma trial showed no difference in
treatment outcomes for patients taking salmeterol who had
different B16 genotypes, according to a report in the Nov. 21
issue of The Lancet.
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Sleep Apnea in Kidney Transplant Patients Assessed
The prevalence of obstructive sleep
apnea in patients with kidney disease who underwent or are
awaiting transplant is similar, but transplant recipients with
the sleep disorder may be at higher risk for hypertension,
according to a study published online Nov. 18 in the
Clinical Journal of the American Society of Nephrology.
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Study Suggests Treatment for Down's Syndrome
Treatments that address deficient
norepinephrine-mediated neurotransmission could treat cognitive
dysfunction in Down's syndrome, according to the results of
animal research published in the Nov. 18 issue of Science
Translational Medicine.
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Video Found to Be Useful in Pelvic Inflammatory Disease
Adolescent girls who watch a
community-specific video intervention at the time of diagnosis
of pelvic inflammatory disease may be significantly more likely
to have their sexual partners treated, according to a study
published online Sept. 4 in the Journal of Pediatric and
Adolescent Gynecology.
